Publications

Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice

Alsamman, S., Christenson, S. A., Yu, A., Ayad, N. M. E., Mooring, M. S., Segal, J. M., Hu, J. K.-H., Schaub, J. R., Ho, S. S., Rao, V., Marlow, M. M., Turner, S. M., Sedki, M., Pantano, L., Ghoshal, S., Ferreira, D. D. S., Ma, H.-Y., Duwaerts, C. C., Espanol-Suner, R., Wei, L., Newcomb, B., Mileva, I., Canals, D., Hannun, Y. A., Chung, R. T., Mattis, A. N., Fuchs, B. C., Tager, A. M., Yimlamai, D., Weaver, V. M., Mullen, A. C., Sheppard, D., Chen, J. Y. Sci. Transl. Med. 2020 Aug 19; 12:557. DOI: 10.1126/scitranslmed.aay8798

Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells.

Chen JY, Newcomb B, Zhou C, Pondick JV, Ghoshal S, York SR, Motola DL, Coant N, Yi JK, Mao C, Tanabe KK, Bronova I, Berdyshev EV, Fuchs BC, Hannun Y, Chung RT, Mullen AC. Sci Rep. 2017 03 21; 7:44867. DOI: 10.1038/srep44867

Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins.

Zhou C, York SR, Chen JY, Pondick JV, Motola DL, Chung RT, Mullen AC. Genome Med. 2016 Mar 23; 8(1):31. DOI: 10.1186/s13073-016-0285-0

HCV and HIV co-infection: mechanisms and management.

Chen JY, Feeney ER, Chung RT. Nat Rev Gastroenterol Hepatol. 2014 Jun; 11(6):362-71. DOI: 10.1038/nrgastro.2014.17